From plant residues to vaccines: DiP-PhosFect develops innovative biotechnological processes for the production of improved vaccine excipients from lecithin.
New vaccines from plant residues
What is a by-product of the production of vegetable oils could improve the vaccines of the future: lecithin. The DiP-PhosFect project is developing a biotechnological process to produce better-tolerated lipids for vaccines.
At the Leibniz Institute of Plant Biochemistry in Halle, an innovative technology is being developed that combines artificial intelligence with biotechnology. AI helps to optimize enzymes that can specifically convert lecithin into biocompatible vaccine lipids. A special focus is on practical application: The lipids developed for use in mRNA vaccines are being tested in cooperation. Fraunhofer CBP supports the transfer of production to an industrial scale.
By combining artificial intelligence, biotechnology and vaccine development, DiP-PhosFect strengthens the regional pharmaceutical industry and creates new economic prospects for Saxony-Anhalt. The project shows how sustainable technologies and digital innovations can shape the biotechnology of tomorrow.
• Development of improved vaccine lipids from plant residues
• Optimization of enzymes through AI-supported methods
• Establishment of a sustainable production process
• Testing of lipids in vaccine formulations
• Innovative process for enzyme recycling
• Development of new bioeconomic value chains
The work of the Dippe group focuses on enzymatic reactions that will be used for lipid production. Here, in cooperation with subproject B, new enzymes are generated that can generate a wide variety of lipids for subsequent testing by an industrial partner. In addition, technical parameters of production, such as recycling of the enzyme, are investigated using a patented process.
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